Type 2 Autoimmune Hepatitis Triggered by Hepatitis A Virus: A Case Report

Hachim, Ghita and Ourrai, Abdelhakim and Radi, Abdelilah and Lamalmi, Najat and Abilkassem, Rachid and Mohtarim, Rihane El and Hassani, Amal and Agadr, Aomar (2022) Type 2 Autoimmune Hepatitis Triggered by Hepatitis A Virus: A Case Report. Asian Journal of Pediatric Research, 9 (2). pp. 21-25. ISSN 2582-2950

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Official URL: https://doi.org/10.9734/ajpr/2022/v9i230264

Abstract

Autoimmune Hepatitis (AIH) pathogenesis is still unknown. However, among patients who have a genetic susceptibility, some viral infections appear to be triggers for AIH.

We report a case of a child who developed type 2 autoimmune hepatitis as a result of HEPATITIS A Virus (HAV) infection.

An 8-year-old female who was diagnosed with hepatitis A three years ago and was cured after three months. She developed jaundice and epistaxis a few years later.

Complementary tests revealed polyclonal hypergammaglobulinemia, antinuclear and anti-LC1 antibodies, and hepatocyte necrotico-inflammatory lesions in a liver biopsy. The diagnosis of type 2 autoimmune hepatitis was kept.

A remission was obtained under corticosteroid and azathioprine treatment.

In cases of persistent HAV infection, AIH should be investigated so that therapy can start earlier. To prevent more serious complications, AIH patients should also receive the Hepatitis B Virus (HBV) and HAV vaccines.

Item Type:	Article
Subjects:	Oalibrary Press > Medical Science
Depositing User:	Managing Editor
Date Deposited:	30 Jan 2023 08:30
Last Modified:	26 Jul 2024 06:25
URI:	http://asian.go4publish.com/id/eprint/1162

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