Cardiospermum halicacabum Linn. - A Review of its Medicinal Effects on Human Healthcare System

A current revision based on medicinal effects on the human healthcare system regarding Cardiospermum halicacabum Linn. herb comes under the family Sapindaceae and frequently known as Balloon vine. It can be seen in tropical and subtropical areas mostly. Mainly used for rheumatism treatment for several centuries. Other than rheumatism treatment, it is widely used to treat snakebite and stiffness of limbs. Ayurvedic form of medicine and folk form of medicine was prepared from this herb and also widely used. From various parts especially the root, stem, leaves, and seed of this herb contains plenty of bioactive compounds and widely used as food and medicine to cure lots of disorders. Ethanolic extract and alcoholic extract of various part of this herb are used for many pharmacological activities like antibacterial and anti-biofilm properties, to treat ethanol induce gastric ulcer in rats, protective role against STZ induced diabetic rats, and fertility of male rats using leaf extract, the antiparasitic activity of extract using in vivo method, antioxidant and anti-inflammatory properties by ex vivo and in vivo method, etc. Different evaluation of this herb is done for controlled toxicity and deterioration regarding quality to ensure safety for the usage of this herb in the form of medicines can be taken into consideration for upcoming researchers to develop and apply different methods based on the separation of bioactive compounds for the treatment of different disorders.