EFFICIENT GREEN APPROACH FOR THE SYNTHESIS OF 1, 4-dihydropyridines UNDER SOLVENT-FREE CONDITIONS ADOPTED IN INDIA: A SYSTEMATIC REVIEW

The 1,4-Dihydropyridine derivatives are a class of compounds having diverse applications in the biological world. Seeking the importance of this class many methods have been developed to synthesize the desired products in diversified manners. As some of the very important derivatives are used for medical purposes, most of the researchers are looking for more convenient, efficient, and environmentally benign methods. This review concentrates on the solvent-free methods for the synthesis of derivatives specifically used in India, to acknowledge the efforts and contribution by the Indian researchers, also discussing the catalyst used, conditions, percentage yield, and some of the advantages-disadvantages. A systematic approach was selected to search the different databases.