ANTIBACTERIAL, ANTIFUNGAL ACTIVITY AND CHEMICAL COMPOSITION STUDY OF ESSENTIAL OIL OF Salvia officinalis FROM THE SOUTH ALGERIAN

Extraction of essential oils from Salvia officinalis plants was carried out using steam-distillation Method. We did this study to obtain an extract essential oil from the plant Salvia officinalis South region Algerian cultivated to the Municipality of Ghardaia. The Salvia officinalis, widespread in Algeria, of the family Lamiaceae is a native herb of several therapeutic properties (antiseptic, anti-neuralgic, analgesic...). The extraction of its aromatic fraction offers new perspectives in aromatherapy by hydrodistillation method by a Clevenger-type apparatus. The extract obtained was the subject of Antibacterial and antifungal activity and a chemical study includes determining the chemical essential oil composition by GC-MS which showed the product exsistance which might present different interests. The Antibacterial and antifungal activity of oils was tested using the direct contact method against the growth of different Fusarium (Fusarium sporotrichioides Fusarium graminearum and Fusarium langsethiae). The results showed great potential of natural antimicrobial activity against strains tested. The analysis of this oil by GC-MS were identified Thirty four compounds representing a percentage of 75,46% of the essential oil of Salvia officinalis, lets notice the presence of several components which Camphor (23.3%), Followed by α-Thujone (14,6%), 1.8-Cineole (5,72%), and Limonene (4,04%) are the major components. It would be interesting to conduct further study on this plant and other medicinal plants to isolate, purify and identify the active ingredients with biological activities.