Determining the Effects of Methanolic Extracts of Quisqualis indica on Passive Smoking Induced Hyperlipidemia in Rats

In the present study we will compare the hypolipidemic activity of methanolic and aqueous extracts of aerial parts mainly flowers of Quisqualis indica (QI) on passive smoking (PS) induced hyperlipidemia in rats which had been evaluated. Passive smoking in a confined chamber with one burning cigarette inside caused hyperlipidemia. The hypolipidemic activity was determined by measuring the level of blood serum in UV at 505 nm after treatment with the reagent included in the auto span diagnostic kit. Using distilled water, a dose of Methanolic and aqueous extracts of QI was produced, i.e. 100 mg/kg p.o. Both QI extracts considerably lower the toxic lipid layer in blood serum at various concentrations and doses, indicating that the plant has hypolipidemic characteristics. It lowers LDL, VLDL, cholesterol, triglycerides, and raises HDL levels in blood serum to a considerable extent, which could be attributed to the suppression of lipid peroxidation because the plants contain antioxidants. Our result shows that the methanolic plants extracts comparatively are good than Aqueous extract which reduced harmful lipids and also recover the disorders in lipid metabolism noted in hyperlipidemic state.